Principal Investigator/Research Fellow/Director - DMPK
Company: Arcus Biosciences, Inc.
Location: Hayward
Posted on: May 12, 2022
Job Description:
Principal Investigator/Research Fellow/Director - DMPK Arcus
Biosciences is seeking a highly motivated and experienced
individual to join our Drug Metabolism and Pharmacokinetics (DMPK)
Department. The successful applicant will be a key member of our
multi-disciplinary project teams and will be responsible for
leading effective DMPK support to the discovery and development of
novel immunotherapy drug candidates. Title will be commensurate
with experience. Core responsibilities:
- Develop DMPK strategy and drive its execution in support of
Discovery and Clinical Development milestones
- Represent DMPK in Discovery and Development project teams
- Identify and address critical ADME-centric issues
- Provide guidance to Medicinal Chemistry on lead
optimization
- Collaborate with Biology and Translational Sciences to define
PK/PD relationships
- Select and characterize clinical development candidates with
appropriate ADME properties
- Oversee DMPK studies in support of clinical development
- Author and review nonclinical PK sections and study reports for
regulatory submissions
- Manage and/or mentor scientists and research associates
Qualifications:
- Ph.D. degree in pharmacokinetics, pharmaceutical sciences, or
related discipline with 6+ years of industrial experience
- In-depth understanding of DMPK principles and demonstrated
ability to integrate information, from both literature and internal
research, for addressing ADME-related issues
- Experience supporting the discovery and development of drug
candidates as a DMPK representative gained in an appropriate
industrial environment
- Experience in the preparation of regulatory documents and
familiarity with DMPK-related regulatory guidance
- An established track record as a highly collaborative team
player who works effectively on cross-functional project teams and
builds strong relationships with key stakeholders
- Strong work ethic and organizational skills
- Experience managing and mentoring junior scientists and
research associates Arcus Biosciences is an equal opportunity
employer.
Keywords: Arcus Biosciences, Inc., Hayward , Principal Investigator/Research Fellow/Director - DMPK, Executive , Hayward, California
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